Buy Ataluren Online
Buy Ataluren online is a novel, orally administered drug that targets nonsense mutations. Ataluren is approve for use by the European Medicines Agency to treat Duchenne Muscular Dystrophy in patients aged 5 years and older who are able to walk. More specifically, ataluren is use in the small group of patients whose disease is cause by a specific genetic defect (call a ‘nonsense mutation’) in the dystrophin gene. in addition to, This drug does not yet have approval by the US Food and Drug Administration or by Health Canada for any indications.
furthermore, This international phase III trial, lasting 3 years (one and a half double-blind and one and a half years open) has been completed in France. It is still ongoing internationally for the open-label phase of the trial.
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moreover, This double-blind, placebo-controlled phase III trial followed by an open-label section aims to evaluate the efficacy and safety of 40 mg / kg / day ataluren in 250 boys with Duchenne muscular dystrophy ( DMD) and never received ataluren. This trial, still ongoing internationally, has been completed in France. Buy Ataluren online
equally important, Ataluren (PTC124) is a molecule that allows the cellular machinery to bypass premature stop codons in genes (read-through), to manufacture the corresponding functional protein. The results of a phase IIa trial evaluating several doses of ataluren, including that of 40 mg / kg / day, in people with Duchenne muscular dystrophy, showed that this molecule made it possible to produce dystrophin in the muscle and was well tolerated. Buy Ataluren online
Who is concerned ?
in addition to, Boys with Duchenne muscular dystrophy with a mutation leading to a premature stop codon, aged 7 to 16 years, who have never received ataluren and who have been treated with glucocorticoids for at least 6 months from the date of start of treatment of the test. Buy Ataluren online
How did the test go?
not only-but also, Patients received ataluren orally every day for 48 weeks (11 months). Follow-up continued for up to 56 weeks.
Regular visits made it possible to assess the efficacy and tolerance of the product. Examinations and tests make it possible to check whether the product was well tolerate. And well assimilate by the body and to follow the evolution of the ability to walk and motor skills. Buy Ataluren online
Where did the trial take place in France?
• in the second place, This international multicentre trial took place in France and in several European countries (France, Belgium, Germany, Italy, Spain, Sweden, United Kingdom, etc.). Where it has ended and in Australia, Brazil, Canada, Chile, Republic of Korea, United States, etc., where open-label expansion continues.
• consequently, In France, the trial took place in 4 research centers. Paris, Institute of Myology, Pitié Salpêtrière Hospital and Necker Hospital; Marseille, La Timone Hospital; Nantes, CHU Hôtel Dieu. Buy Ataluren online
Who is the sponsor of the trial?
in the same way, The pharmaceutical company PTC Therapeutics is the sponsor of this trial. As a result, Buy Ataluren online.
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